Review Article PRENATAL DIAGNOSIS OF GENETIC DISORDERS
نویسندگان
چکیده
Reprint request: Dr. M.L. Kulkarni, Professor of Pediatrics, 2373, MCC A Block, Davangere 577 004. methods of obtaining fetal tissues for karyotype, DISFA studies and enzyme assay(4). The procedure is done at 8-11 weeks of gestation. The transcervical sampling involves insertion of various types of catheters transcervically under ultrasound guidance for aspiration of chorionic villi. Transabdominal CVS is preferred as it can be done even in the second trimester of pregnancy and is associated with lesser risk of infection, bleeding and pregnancy loss(5). CVS can be done in the second or third trimester of pregnancy by direct aspiration of placental villi through transabdominal route under ultrasound guidance.
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